V2EX aromatase inhibitor

Aromatase Inhibitor

定义 Definition

芳香化酶抑制剂:一种通过抑制芳香化酶(aromatase)来减少体内雌激素(estrogen)生成的药物类别,常用于激素受体阳性乳腺癌(尤其是绝经后人群)的治疗或辅助治疗。常见药物包括 anastrozole、letrozole、exemestane。(该词组在药理与肿瘤学语境最常见;在其他领域也可能有延伸用法。)

例句 Examples

She started an aromatase inhibitor after surgery.
她在手术后开始使用芳香化酶抑制剂。

In postmenopausal patients with hormone-receptorpositive breast cancer, an aromatase inhibitor may reduce the risk of recurrence by lowering estrogen levels.
在绝经后、激素受体阳性乳腺癌患者中,芳香化酶抑制剂可通过降低雌激素水平来减少复发风险。

发音 Pronunciation

/romtez nhbtr/

词源 Etymology

aromatase 来自 “aroma-(芳香/芳香族)+ -ase(酶)”,其中 -ase 是生物化学中表示“酶”的常见后缀;inhibitor 自拉丁语词根,意为“抑制者/抑制物”。合起来即“抑制芳香化酶的物质/药物”。

相关词 Related Words

文学/著作中的使用 Literary Works

  • Harrison’s Principles of Internal Medicine(《哈里森内科学》;内分泌与肿瘤治疗相关章节中常见该术语)
  • DeVita, Hellman, and Rosenberg’s Cancer: Principles & Practice of Oncology(经典肿瘤学教材;乳腺癌内分泌治疗部分常见)
  • Goodman & Gilman’s The Pharmacological Basis of Therapeutics(《古德曼&吉尔曼药理学》;药物机制与分类中常见)
  • The Emperor of All Maladies by Siddhartha Mukherjee(《众病之王》;大众医学叙事中讨论乳腺癌治疗进展时常涉及此类药物概念)
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